- Empoli are unbeaten in Serie B at home (W1, D4).
- Empoli have scored 0.5 goals per game in recent head-to-heads against Sampdoria, who have averaged 1.0 as visitors.
- Empoli have drawn three in a row at home (D3).
Empoli and Sampdoria will play a game of contrast
Empoli are locked in mid-table obscurity in Serie B with 10 points from nine games in 2025-2026 and they’ll need a spark to propel them into the promotion race. Alessio Dionisi took charge of the club on October 16, 2025 and needs to inject energy and some tactical clarity into the squad after a shaky start to the season.
The Blue and Whites come into this midweek game after 1 win, 3 draws and 1 loss in their last five, including a 1-2 away defeat at Modena and a 1-1 home draw with Venezia.
Sampdoria are stuck in 18th place in Serie B after taking five points from their opening eight games so they will be happy for the chance to play Empoli on Tuesday. Massimo Donati has been the coach since July 2025 but the recent managerial upheaval at Sampdoria has meant the players have had little time to gel and results have suffered.
This Empoli vs Sampdoria preview highlights how the Blueri are in decent form of late, with one win, two draws and two defeats in their last five, which includes a 4-1 win at home to Pescara and a 3-1 defeat away to Virtus Entella.
Sampdoria are in a battle
Sampdoria beat Empoli 2-0 away from home in a friendly back in 2025 and have won one and drawn one of the last two head-to-heads. Our Empoli vs Sampdoria prediction suggests Empoli are the 2.3 favorites to take the win here, with Sampdoria the 3.2 underdogs and the draw at 3.1.
Empoli will be the team on the front foot in this clash as they use a 4-3-3 system to push up the pitch and put pressure on the Sampdoria defence. The visitors prefer a more compact 4-2-3-1 which allows them to stay deep and contain their opponents, with a double pivot protecting the defence and a pragmatic style of play.
The Empoli vs Sampdoria prediction is also reflected in the odds, and backing under 2.5 goals at 1.53 seems a good starting point for this Serie B clash as both sides have been playing a defensive game of late and Sampdoria have struggled to score away from home.
Stiven Shpendi has been a threat since joining Empoli and has three of their seven goals in the last five games, while Rares Ilie is the creative hub in the middle of the park with three assists in the same games.
Fabio Depaoli has chipped in with two of Sampdoria’s six goals from midfield in their last five and Massimo Coda leads the line with three goals in eight Serie B games.
Empoli are at their best at home and haven’t lost in Serie B in front of their own fans this term, averaging 1.60 goals scored per-game and conceding an average of 1.20. Sampdoria haven’t won on the road in Serie B this year, taking just one point from their last three and have struggled to score on the road. Our Empoli vs Sampdoria betting tips conclude that the hosts should have enough to edge a tight game on Tuesday and we’re in agreement with the odds here. For those looking for more detailed analysis, the Empoli vs Sampdoria prediction is for a home win in a close contest.
