- Estudiantes de la Plata are second in Copa Libertadores Group A with 1 point from their opening game.
- Cusco FC are bottom of the group, having lost their opening Libertadores game.
- Estudiantes are 2 wins, 1 draw and 2 defeats in their last 5 games in all competitions.
Estudiantes have a solid home advantage
Estudiantes de la Plata are priced as heavy favorites to see off Cusco FC in their upcoming Copa Libertadores, Group A clash on Tuesday night and the Estudiantes de la Plata vs Cusco FC prediction is that the Argentine giants should have enough quality to see off the Peruvian challengers.
Alexander Medina has had a positive impact on the side since taking over in February 2026, instilling a pragmatic, structured approach to the game and a disciplined 4-2-3-1 or 4-3-3 formation that suits the squad.
Medina’s men are solid at the back, build play well through the midfield and are very dangerous in the transition, particularly when they hit the front with their forwards and wingers.
They have had mixed results across all competitions recently, with two wins, one draw and two defeats in their last five, but are 1 win and 1 defeat in their last two at home.
Cusco FC, on the other hand, are in good domestic form, coming into this game with three wins in their last five, but they were beaten in their Libertadores opening group game.
This Estudiantes de la Plata vs Cusco FC preview outlines a match that is expected to be highly competitive given both teams' current form.
Cusco are a lively and ambitious team
Alejandro Orfila has been a breath of fresh air since taking over as head coach in March 2026. He plays an energetic, pressing game, where his players press the ball high up the field and create goal-scoring chances, particularly when they can stretch play.
They have won their last two away from home in Liga 1 - Apertura, including a 3-1 win over FBC Melgar Arequipa, so they could certainly trouble their opponents in the attacking third.
But they could become frustrated by a more organised and patient Estudiantes outfit that will be content to play a cautious, defensive game.
For those looking for Estudiantes de la Plata vs Cusco FC betting tips, it’s worth considering how Cusco’s attacking approach might clash with Estudiantes’ defensive strengths.
Expect an intense, low-scoring game
We’re expecting Estudiantes to edge out Cusco in a tactical matchup and feel the Estudiantes de la Plata vs Cusco FC prediction heavily favors the Argentine side, playing at home, who should have the advantage.
The odds of 1.27 for an Estudiantes win don’t appeal to us, though, and we’re taking Both Teams to Score - Yes at 2.55, but we also feel the game could be a tense and low-scoring battle.
Tiago Palacios is the dangerman for the home side, scoring three of Estudiantes’ last eight goals and netting once in their opener in the Libertadores. Facundo Callejo is the main threat for Cusco, who have scored four of their last seven in all competitions.
Cusco should nick a goal on the counter-attack, but the two defences should hold firm enough to allow Estudiantes to earn the victory, so based on our Estudiantes de la Plata vs Cusco FC prediction, we’re also taking Total Score Under 2.5 at 1.83.
Estudiantes hammered Central Cordoba De Santiago 5-0 at home two weeks ago in Liga Profesional - Apertura 2026, so don’t underestimate their attacking potential in this one.
Mikel Amondarain has brought an extra spark to the team’s creative play, providing an assist in their group opener.