- Estudiantes de la Plata are 2nd in Copa Libertadores Group A with 5 points from their 3 games.
- Cusco FC are bottom of Copa Libertadores Group A with 0 points from their 3 matches.
- Facundo Callejo has scored 4 goals in Cusco FC’s last 6 games (all competitions).
Estudiantes eye up a vital away win
This Cusco FC vs Estudiantes de la Plata preview finds Estudiantes de la Plata 2nd in Copa Libertadores Group A after 3 group stage games, and they head to Cusco to face the section’s bottom team on Wednesday.
The Argentine side won the reverse game against Cusco FC 2-1 two weeks ago to move themselves into the top two and the Peruvians have their work cut out to reverse that result.
This Cusco FC vs Estudiantes de la Plata prediction suggests that Cusco have won two and lost three of their last five games in all competitions and although they have two straight home wins in domestic competition, their continental form is lacking.
Callejo the danger man for Cusco
Cusco have lost their only home game in this competition, failed to score and conceded two goals, and they have the firepower but not the quality to trouble the Argentine’s backline.
Facundo Callejo has been on a hot streak in Cusco colours with four goals in their last six and the number ten is their best chance of getting on the scoresheet on Wednesday.
Our Cusco FC vs Estudiantes de la Plata betting tips highlight that Diego Soto is the creative force in midfield, with one assist in three Copa Libertadores games so far, but the home side may have to defend deep for large periods as Estudiantes press forward.
Visitors’ pressing can pinch possession
Cusco line up in a 4-3-3 system with Alejandro Orfila, who has emphasised structure and staying compact since taking over in March 2026, while Alexander Medina’s men operate in a flexible 4-2-3-1 or 4-4-2 which has been very effective since February of this year.
Estudiantes are an aggressive team that press opponents and play vertical football, although they can be caught out on the break when they are too far forward.
There is a good chance that at least one of these two teams will fail to score, and the Cusco FC vs Estudiantes de la Plata prediction is for Estudiantes to eke out a narrow win in this away fixture.
The visitors, who have drawn two and won one of their three group games, have conceded just one goal in their only Copa Libertadores away match and will get the win at odds of 2.47.
‘Both teams to score - No’ can be backed at 1.73 and ‘Under 2.5 goals’ is 1.59, although there is a slight preference for the win bet in this game.
Tiago Palacios is the main goal threat for Estudiantes with two in the group games and they are expected to control the game and earn the three points that will keep them in the top half of the group for another match.